Transfusion Transmissible Infections
Regardless of advancement in screening technologies while blood transfusion, there is still a risk of transfusion-transmitted infectious diseases. These infectious diseases can be reduced by donor exclusion, screening for serological infection markers or nucleic acid testing (NAT) by viral gene amplification. Nevertheless, blood-borne infection is transferred through transfusion of infected blood donated by apparently healthy and asymptomatic blood donors. Infectious agents involved are of various types which include-
- Hepatitis B (HBV)
- Hepatitis C (HCV)
- Human immunodeficiency (HIV-1/2)
- Human T-cell lymphotropic (HTLV-I/II)
- Cytomegalovirus (CMV)
- West Nile (WNV)
- Trypanosomiasis
- Transmissible Spongiform Encephalopathy (TSE)
- Malaria and Dengue Viruses